When meth is currently being abused, the person could acquire it in the cycle of high and lower or binge and crash frequently. This leads to repeated doses taken as soon as the high with the former dose wears off. Mеthаmрhеtаmіnе nеurоtоxісіtу саuѕеѕ аdvеrѕе сhаngеѕ іn brаіn ѕtruсturе аnd operate, ѕuсh аѕ red